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February 16, 2026 - They do not admit you are better, so they
pretend you are not part of the story. But they cannot deny you are
better, so they come running when they need something done right.
Same pattern every time, and it always comes from the same place:
their insecurity.
January 28, 2026 - Yes, Money Heist fans, the building shown in
this
photograph is where the first
seasons of the series were filmed. But in real life, it is the
building that houses the headquarters of the Spanish National
Research Council (CSIC). And there, in its impressive offices
paneled in fine wood, the present and future of its many institutes
and employees are decided every day. And why are we bringing this up
here and now? Well, because, as the eternal
Sam Cooke would say, a change is gonna come.
January 26, 2026 - In the April 9 issue of JACS,
Ma and Clardy
described a mechanism for cleavage of the plasmalogen's vinyl ether
to generate an 1-lysophosphatidylethanolamine under conditions that
mimic inflammatory environments. Migration of the fatty acid at sn-2
to sn-1 yields a 'classical' 2-lysophosphatidylethanoloamine which,
if carrying oleic acid, could work as an endogenous activator of the
nuclear hormone receptor RORγt (retinoic-related orphan receptor
gamma). Although its relative contribution compared with
phospholipase A2‑mediated
hydrolysis remains unresolved, this plasmalo- gen‑triggered route
reframes how these lipids may function as regulated reservoirs for
immune signaling. Due to its implications for plasmalogen biology,
we selected this study as our 2025 Paper of the
Year.
January 22, 2026 - Continuing our quest for plasmalogen
recognition, it was time for a short
seminar on plasmalogens at the
Rare Diseases Network
we belong to. What they do and what they don't do in innate
immunity.
January 20, 2026 - In a research group, intellectual diversity
is a strength. It does not matter whether people think the same way
as someone else. What matters is that they think at all, that they
question, reason, and engage with ideas instead of waiting for
answers. At this point, any genuine, active thinking is a victory.
January 16, 2026 - The protein kinase C family has been on the
scientific stage for decades and many of its physiological and
pathological roles are already well mapped. Yet there is still room
for surprises. One isoform in particular, PKCϵ, turns out to play a
remarkable part in shaping calcium signaling in macrophages. Curious
about how this works and why it matters? Discover the story
here.
January
11, 2026 - "What embitters the world is not excess of
criticism, but an absence of self-criticism" (Gilbert K.
Chesterton, English author and philosopher). Winter 2026 group
meeting schedule here.
December 23, 2005 - Someday, people may wake up and recognize
that plasmalogens are among the
most beautiful things Mother Nature has given us. As the New Year
approaches, that remains our heartfelt wish for the times ahead.
December 18, 2025 - Asking individuals with openly strained
relationships to pose together in a photograph "for the occasion"
prioritizes the appearance of harmony over the actual reality of the
institution. The result is a memory that everyone present recognizes
as false. It may not be malicious, but it is profoundly tone-deaf.
December 15, 2025 - Most definitely, it feels as though
our beloved institution is always one step behind where they should
be. Appointments scheduled for next year sound reasonable, but they
still seem to arrive a bit too late.
December 12, 2025 - The SPM (specialized pro‑resolving
mediators) field is riddled with conflicting results. With so many
interests at play, it is no surprise that, as
someone once wrote, "no one expects an easy resolution to this
highly inflamed dispute." Anyway, yesterday we were invited to
present at an SPM meeting in Madrid,
which we did, and the atmosphere was genuinely enjoyable. We
presented on palmitoleic acid though, not really part of the SPM
fray.
.
December 11, 2025 - Lipins once again featuring prominently,
this time in the monthly webinar of the rare diseases network to
which we belong. Pic here.
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